摘要
羧酸具有无毒、廉价易得、稳定易存储等特点, 有关过渡金属Pd催化(杂环)芳基羧酸脱羧的偶联反应在本世纪来得到了迅速发展, 大有取代传统偶联反应之势. 本文综述了Pd催化(杂环)芳基羧酸脱羧与多种底物的偶联反应, 如烯、芳基卤化物、芳烃, 三氟芳基硼酸盐等底物, 并对相关的反应机理进行了探讨.
Abstract：
Since carboxylic acids have distinguishing features of non-toxicity, low cost, ready availability and easy storage, Pd-catalyzed decarboxylative coupling reactions of (hetero)aromatic carboxylic acids have been obtained rapid development since this century, and have exhibited a tendency toward replacement of traditional coupling reactions. The coupling reactions of Pd-catalyzed decarboxylation of aromatic carboxylic acids with various substrates of olefins, aryl halides, arenes, aryltrifluoroborates and etc. are reviewed, and the relevant reaction mechanisms are discussed.
付拯江, 李兆杰, 熊起恒, 蔡琥. Pd催化(杂环)芳基羧酸脱羧的偶联反应研究进展[J]. 有机化学, 2015, 35(5): 984-996
